hey orbital , that is a truly amazing article that you've posted.
Despite the fact that it works for mice only , so far....
Untill now fibrosis and scarring of the corpus cavernosum was totally irreversible, if such a fibrosis was pinpointed to be the cause of your erectile dysfunction, than your only remaining option would be a "penile implant".
That article sparks some hope to reverse it AND it also totally corelates with the studys i posted: Those where hundreds of guys were given viagra daily for 3 - 6 month and after that their erections (tumescence + bloodflow) considerably improoved - most importantly , Penis EnlargementRMANENTLY, they did not have to take viagra any longer to keep the effects after the test duration..
@jtmorgan10
""""This is totally fucking up my life. I had an awesome life before I got into Penis Enlargement, but now I feel like I am on the brink of suicide all day because I have a gorgeous girlfriend who I thought I might possibly marry. We could have had a wonderful life potentially. I know our relationship won`t last much longer and I don`t know how I am going to be able to get on with my life knowing that I may likely be effectively impotent for the rest of my life. Viagra doesn`t even really make a difference for me. This whole situation has devastated me, and I`m sure you guys can relate."""""
---> Man, listen. I totally feel what you are saying there, I've been there, with exactly the same mindset, thoughts, also in a long term relationship, I can totally relate to everyting you say. Now since, alot of time passed since then let me tell you one thing...eventhough it may SEEM to you as the END of the WORLD and your life for you - ITS NOT..its just a phase and you will eventually get through it, the sooner, the better...infact I really stress the word SEEMS...it only appears to be so bad because you think about this and only this ED problem of yours ALL the day AND whats even worse you are relating your relationship problems and most probably EVERY problem that you have or MIGHT get in the future to ED. (You worry about things you cannot control like the past or the future)
Do not dwell on it. I understand its hard for you because you are probably young and your mind hasn't matured enough to cope with stress like that. Thats why this this problem takes up all your universe...
..lemme give you some simple advice to get you started feeling good again AND get you on the right track to recover.
1. Accept the fact that you have ED. Stop thinking about it as your BIGGEST and only problem and the missing puzzle to a succesfull life. Only YOU can effectively hinder yourself from achieving those "goals/ dreams" in life that you mentioned <<<"We could have had a wonderful life potentially. I know our relationship won`t last much longer and I don`t know how I am going to be able to get on with my life knowing">>> Notice how you keep mentioning yourself and her or both of you ? Thats because IT IS UP TO YOU AND HER to make it last. Your dick is probably the least important factor in a possible future marriage or the current relationship. You just allow it to get to you, and once it gets you down it reflects on everything else...but only because YOU let it happen !!! Every second marriage gets cancelled after 1 year of marriage. Do you think its because all those guys had ED ? Hell no , its due to cummunication problems/inabilitys/weak charakters/lack of personality/commitment/ WORK !!!!!! and so on.
2. GAIN KNOWLEDGE. Know your enemy ! Pinpoint the reason behind your ED. Don't obsess, inform yourself !
You are obviously lacking alot of knowledge when it comes to ED, you need to do much better research - I promise, the more you know, the less you will have to worry about things (you didn't know before and still feared them).
Hint: The knowledge and all possible reasons and also all up-to-date cures were already researched by me and others on this forum , you can find the information in my posts (clicking on profile and clicking on "view all posts or threads by tbirdy).
If you did so you wouldn't say things like :
" I may likely be effectively impotent for the rest of my life." Well did you know that you could get an instant cure by a modern undetectable penle implant that totally simulates a real erection and your orgasms and sensivity remains the same , so ? What do you fear.
That above is highly unlikely and definetly not neccessary for you right now, but its still a possible fix to a possible condition in the future wich you wouldn't worry about if you knew about the cure.
another example ?
"Viagra doesn`t even really make a difference for me."
Well DID you even try that 3 - 6 month daily 50 mg before sleep routine as mentioned in the study done in 2005 that effectivly cured many many men with medium erectile dysfunction ( exactly what you have) ???
Besides, I have a feeling that you are either unconciously shitting yourself or me :
You say viagra doesn't really make a difference AND that your dick is oh so fucked up but then last time you tried :
"The last time I tried, I could get almost a full erection with oral sex before penetration, but I only get half erections at night and spontaneously, and they are very weak and rubbery because my dick has somehow been deformed inside. The head is often cold, and I have discoloration."
You fucking got it up had sex , had nighttime and spontanious erections...WTF ? Seems like light to medium ED to me and that eventhough it doesn't work 100% like it used to , it still works !!!!
So how can you be devasted ? Pls totally shut the fuck up bout even mentioning suicide ??? What the hell ??? What for ?
You do know that viagra at any dosing STILL needs a sexual stimuls ( you need to feel the urge and get turned on) in order to work ??? So do yourself a favour : Don't touch your dick for a week (as in no mastuarbation ejaculation) then plan a romantic day with your girl , nice dinner and shit , take 100 mg viagra 2 hours before (the 2 of you prbably get down) get a blowjob from here , and THEN come back telling me viagra didn't make a difference...
Well ok now , I don't want to be to harsh, just trying to get your head straight again...you should have nuff inout and ideas to get you started in the right directions...
BACK TO THE ARTICLE :
"When L-arginine (2.25 g/kg/day), pentoxifylline (10 mg/kg/day), or sildenafil (10 mg/kg/day) was given individually in the drinking water for 45 days to rats with a PD-like plaque induced by TGF beta1, each treatment resulted in a 80-95% reduction in both plaque size and in the collagen/fibroblast ratio, as determined by Masson trichrome staining. Both sildenafil and pentoxiphylline stimulated fibroblast apoptosis within the TA. Our results support the hypothesis that the increase in NO and/or cGMP/cAMP levels by long-term administration of nitrergic agents or inhibitors of PDE, may be effective in reversing the fibrosis of PD, and more speculatively, other fibrotic conditions."
Jeeez,
L-arginine (2.25 g/kg/day), pentoxifylline (10 mg/kg/day), or sildenafil (10 mg/kg/day) was given individually in the drinking water for 45
In humans =
I would need 191,25 g Argnine , 850 mg of pentoxifylline,
and or 850 mg Viagra....
Ok obviously it doesn't translated from mice to humans without killing the human with the above combo...
so I think what would do the trick is taking the highest allowed/confirmed non poison dosing of each drug daily.
Viagra = Confirmed 100 max , but probably 150 spread throughout the day will be possible.
l-arginine 6-15 grams per day.
and only the pentoxifylline is no problem because an adult can take up to 1200 mg in 3 dosings spread though the day...
Well since all of these drugs do fuck with your blood pressure and heart beat (lowering one and upping the other) its probably safest to try this routine with 10 g arginine and 1200 mg pentoxifylline daily and see what it does for you after a month or 2...
This totally looks like the next step in the right direction:
The studys I mentioned used only viagra for 3-6 month and got great results,
its also proven that l-arginine helps with erections if taken in dosing above 3 grams for a long enough time..so both of them combined would probably have a synergetic great effect. This wasn't tried yet and I can#t tell if its safe to try in the future because each of these drugs do lower your blood pressure significantly and if combined , you could drop dead...
so take care if your willing to try...i wouldn't do this without daily control by a trustworthy doctor that monitors all your body functions especially your heart....
besides , who says you couldn't get the same "mice" effect on humans with 50 mg viagra and 3 grams l-arginine daily...hasn*t been tried yet...
ok, last but not least
IXL and PANDORA
I guess you are trying to help the guys in this thread but what you are doing is equally to: Telling an alcolholic who got in all of his problems BECAUSE OF THE ALCOHOLE , to drink even more , and , better , and harder liquier to solve his problems...
that will not do it
~ peace tbirdy