1. With 'normal' Penis Enlargement, could be that gains are hindered - those are still just observations and not necessarily fact. However, I am trying to gain something else by giving up the production of inflammatory prostagladins (which themselves cause tissue remodelling) -> and that is the ability to clamp long. Thus putting the tunicae under an unnatural amount of stress for a looooong time. WITHOUT killing my penis! My theory (just a theory, not gospel) is that asprin will help me do just that. So far, it has. My own experience is a 50 minute INCREASE (500%) in the time I can spend clamped - and easily too. Just as an aside: 'hypoxic' (low-oxygen) conditions cause the production of nitric oxide and endothelin-1 at a GENETIC level. But more on that when I post a hypothesis based on published scientific material.
2. I really can't say, but it IS possible.
Yes I did.
The first bit is probably spot on. It is what i'm trying to do.
The Bulgarians have a saying, which may sound really simple, but still true in practice: "THE BODY BECOMES ITS FUNCTION". Most Western cultures preach something similar, but rarely practice it: "THAT WHICH DOES NOT KILL YOU MAKES YOU STRONGER". It is the HOW that's important here, and the bottom line is NO adaptation occurs without something happening at the genetic level. THAT is gospel. I'm not talking genetic modification here, but genetic programming.
And just to add some weight to my theory, a recent study confirmed the findings of many previous ones:
Cell Biochem Biophys. 2005;43(3):439-50. Related Articles, Links
Click here to read
Cytoskeletal regulation of nitric oxide synthase.
Su Y, Kondrikov D, Block ER.
Department of Medicine, MSB M452, Box 100225, University of Florida, 1600 S.W. Archer Road, Gainesville,
FL 32610.
The three isoforms of nitric oxide synthase (NOS) endothelial NOS (eNOS), inducible NOS (iNOS), and neural NOS (nNOS) colocalize with the cytoskeleton including actin microfilaments, microtubules, and intermediate filaments directly or indirectly. These colocalizations enable optimal nitric oxide production and help NOS exert their functions. The reorganization of cytoskeletal polymerization state induced by extracellular stimuli such as shear stress, hypoxia, and drugs regulates eNOS, nNOS, and iNOS. Alterations of nitric oxide production caused by cytoskeletal reorganization play an important role in physiological and pathophysiological conditions. This review focuses on recent data regarding the regulation of NOS by the cytoskeleton at transcriptional, posttranscriptional, and posttranslational levels.
Did you warm up beforehand? Did you take the asprin? And did you stay sexually aroused (ultra-important) throughout your session? Those were the main factors for me.
BTW, it seems that my theory may hold some water, but that I am doing things the wrong way around. Since low oxygen causes production of nitric oxide and endothelin, which increases the ability of vessels and penile tissue
to expand (not the tunicae, that I know of though
), this could be a better order to do things in:
1. premedicate with asprin
2. warmup an hour later
3. clamp for five minutes until very engorged
4. do the 3min total clampoff
5. relax clamp, but keep in place (lower pressure than normal clamping) for 15 minutes (try to stay aroused)
6. Clamp at normal pressure for extended period - expansion should be better than the first clamping stint due to the action of the substances that improve blood vessel and penis flexibility
I'm glad that there are sceptics - keeps me thinking - if no-one wants to try the modified version, its OK. I will do it for 2 weeks and report back