Damn brother, that was one long post...

I'll try to explain myself further and possibly address some of your points.

The reason i feel that Androgel is a waste is that if the person that claimed to make great gains from it was using propper dosades as prescribed on it's literature, he was only getting a daily dose of test at either 50mg, 75mg or 100mg depending whether he was prescribed the 5g, 7.5g, or 10g Androgel. Even if he doubled the dose that is still a far cry from what is considered a low dose amoung steroid users. Now if you consider that the actual absorbtion rate of a good transdermals is around 20-50%, then you can see how little actual test you're going to get from androgel. The test contained in Androgel is test base or unesterfied test. Test base has a very short half-life in the body, somewhere in the neighborhood of 12-24 hours. This is why it must be applied at least once a day (bodybuilders that use transdermals typically use 10 times that dose applied several times a day). Most steroid injectables use esterfied test. Esters like cypionate, enanthate, propinate, decanoate, etc. allow the test to be released much slower allowing the test to remaim in the body much longer. It effectively extends the half-life from one day all the way to 20 days or longer. So if a bodybuilder such as myself was taking 10 to 20 times the dose of this person, my dick should be a foot long by now... but it isn't. In fact, i didn't notice any significant gains from Penis Enlargement while is was on IGF-1 and/or steroids. There have also been others on this board that have agreed with me on this.

Another point i'd like to make about testosterone is that directly applying it to any tissue is pointless. No tissue (exo skeletal muscle or cavernous smooth muscle cells) can make direct use of test. Test exerts its effect on muscles thru increased protein synthesis, so you can rub all the test in the world on your dick and nothing will happen. This is why i kept on harping on the local vs. systemic issue. Anyone who claims that rubbing Androgel on your dick will make it bigger is agruing for localized effect which is BS. but even from a systemic perspective, Androgel just does not apply enough test to make much of a difference. I don't care what anyone has to say about making gains from Androgel, it just does not add up.

I believe that gains made from Androgel are due to the power of positive thinking. They hear that other people make gains with it so they apply it and can't help but to work harder. They do in fact make gains but not because of the Androgel but from their efforts. I wonder if the guy who claims to have made great gains from Androgel was an experienced Penis Enlargement'er or was he a beginner... also did he change his routine or do anything different. There are also some that are just fast gainers and whether he used Andrgel or not, he could have made the same gains.

Alternate said:
I was hoping to get some personal comments from Supra and Rydog, as well as as many other people as possible. They were pareticularly mentioned about experimenting with loac and systematic injection of IGF-1.

Here's supra's thread... http://www.mattersofsize.com/forum/showthread.php?t=5540&highlight=igf-1

There are countless examples of all kinds of paradigm and revolutionary changes/findings that seemed completely illogical or unlikely rational/conclusive at first. Ex: The world is flat, we will never fly in space, computers will never be needed for everyday use, you can't make your penis or tits grow at all and you are stuck with what you were born with, the magic bullet killed JFK and there was only one shooter etc etc etc.
Yes this is true but they have all been debunked by science...

The way you present this, seems to justify a very rational and logical response.

1) If you need to convert the test into DHT for growth, how do you increase efficiency of converting test to DHT and having it effect the penis primarily?

2) You insinuate that "a few milligrams" won't make a difference. However, neither will tugging on your dick for only a few hours or days. It seems to me that volume of application may increase chances. The guy who attributed Androgel to his aparent large size did not seem to say that it happened "over night". He may have been consistantly using it for an extended period of time. Same about any other supplement/hormoone/injection/cream etc. Maybe the volume, frequebncy and cumulative time is absolutely essential to discerning results. Actually, it seems that would be the primarily if not soley rational way to discern.

3) I respect your doubts. Still, I do not think that we should be unequivocally conclusive simply because of your current doubts.
You don't want to increase DHT... it has alot of associated side effects that makes it hard to justify. The more severe sides include: androgenic alopecia (male pattern baldness), increased aggresion, and Benign Prostrate Hypertrophy.

Science has proved time and again that tugging on skin, muscles, and ligature does in fact cause them to expand and lengthen. Rubbing Androjel and claiming that it made you dick bigger is not science and in fact contradictory to how testosterone affects tissues.

This insinuates that you know of several studies that you have read which suggest that IGF-1 is increasing penis size whether naturally and or supplementary. The medical exerpt substantiates it.
Yes this is true but we have to put these studies in perspective. Any IGF/HGH study on growth that is performed on prenatal or the young does little for us as the primary role of IGF/HGH in children is to make them grow into adulthood. If you inject HGH in children, they will grow into very tall adults. This has been proven time and again, in fact it is the therapy used on undersized children. That said, if you apply the same therapy to an adult he/she does not get any bigger or taller.
 
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sikdogg said:
Both are a waste... test doesn't directly affect the penis like DHT does. Also what makes you think that rubbing test on your dick will make it grow?? If that was the case, bodybuilders would have overly large shoulders and asses since that is where they inject test and other steroids. Both test and IGF-1 affect the body systemically not locally.


Actually site specific injection does cause the muscles in the injected area to grow.

I am on doctor prescribed steroids and my glutes and shoulders have gotten massive because of the injections.

True it also works systemiclaly, but you do get growth in the areas that receive the high concentration of the hormone
 
Studies do not support localized growth from site injections of steroids...

How long have you been on it as i've been on dozen of cycles and the that has not been the case... frequent injections in the same area can cause temporary swelling due to the depot and typically goes away after a few weeks of either moving to a different site or stopping altogether.
 
I have been doing them for 14 years off and on. Again there is a lot of literature out there says site specific injections into specific muscles increases localized muscle hypertrophy.

Some of the most massive, ripped guys in the world swear by site specific injections

Again I can see the results on my own body and theirs.

You get a higher concentration of AAS in the site
 
I don't claim to be an expert on this stuff, but if there wasn't a localized effect, then why do they make cortisone-analogue creams that are applied directly to the affected area of rashes, etc.? I'm sure there is plenty of systemic effect as well, but there has to be localized effect or otherwise these creams would be no more effective than a tablet of prednisone.

On a side-note, delts on AAS users usually are larger partly because the deltoids and neck muscles are a couple of muscles that have a high concentration of steroid receptors...opposed to say--the lower back.
 
goldmember said:
I don't claim to be an expert on this stuff, but if there wasn't a localized effect, then why do they make cortisone-analogue creams that are applied directly to the affected area of rashes, etc.? I'm sure there is plenty of systemic effect as well, but there has to be localized effect or otherwise these creams would be no more effective than a tablet of prednisone.
You're talking apples and oranges here... treating a rash is not the same as anabolism.

On a side-note, delts on AAS users usually are larger partly because the deltoids and neck muscles are a couple of muscles that have a high concentration of steroid receptors...opposed to say--the lower back.
If this was the case then the neck and delts would be predisposed to gains that outweigh gains made from other bodyparts. Everybody should have well developed neck and delts whether they took steroids or not because there is no such thing as a steroid receptor, there is however an androgen receptor which androgens bind to. Both endgenous and exogenous androgens. I speculate that delts are easily developed because they are a secondary muscle for ALL upperbody exercizes. Anytime you work an upperbody exercize, you are directly or indirectly working your delts.

I wish i was as lucky as THICKEST ONE, cuz i almost always inject gear into my delts and sadly my delts aren't my strongest bodypart.
 
I simply reiterrated what my physiology professor (who earned his Ph.D from The University of California at Berkeley) told me when I asked him this very question. The location of androgen receptors DOES have a large impact on where you will see muscle growth. In your case, you may not have a high concentration of AR in your delts, but the majority of men do. Some men have a high concentration of AR in their scalp...and that is why they go bald while other men don't.
 
sikdogg;160191 said:
The growth in not localized but systemic so i'm not sure if injecting it into your dick will do much.

Also, predisposition to cancer will not accleerate or cause cancer to grow. You must already have cancer in order to accelerate its growth from igf-1.

You know some good stuff about these peptides and chems.
But in the first part I have to tell you, that's not right. If you have genuine igf-1, then it actually has a local effect in the most part, because of the short half-life I'd say maybe a fifth reacts systemic.

the difficulty in that is, getting to real igf-1. I'm sure there would be a synergetic effect with the use of HGH s.c and igf in cc, but still that is not even the magic pill, as it takes a long time
for the cancer part you are right

stuff like supps are limited. and i'd never buy b$ like virgx or so. andractim/dht creme may increase the libido and lead to androgenic effect, but after the age of 14-15 there is no growth to expect
 
psychojitsu;170018 said:
if site injection worked we would all have 100 lb asses.

lol, that was good. stanozolol is the only aas i know of, that causes local growth but with a notable pain.
anyway we are not talking about bodybuilding here.

local is always better than systemic sikdogg, so looking out for a local effective version is not a waste of time. many peptides do have a local effect. unfortunately there is no real scientific research on these substances in relation to tissue repair and growth in the cc

even though we are in 2011, very little is understood about these peptides and in what relation they stand to the smooth muscle composition.

back to igf-1, if it's genuine it has a local effect. (don't know about the lr3, but it should be the same there)
 
I just started my chemical Penis Enlargement routine 2 days ago; 5 IUs quadmix along with 10 IUs (70 mcg) IGF-L3. Later this week will pick up some igf-RH and switch to that. I will go 1 day on, 1 day off as to not dull the igf receptors. Today was day 2; I did 8 IUs of quadmix and 70 mcg IGF-L3. I have massive supplies so I can try for several months. I may even throw in some Andractim topically. Will keep everyone posted best I can, anyone with comments/questions welcome. Im particularly curious if i can further increase the IGF dosage.
 
yakult;478271 said:
I just started my chemical Penis Enlargement routine 2 days ago; 5 IUs quadmix along with 10 IUs (70 mcg) IGF-L3. Later this week will pick up some igf-RH and switch to that. I will go 1 day on, 1 day off as to not dull the igf receptors. Today was day 2; I did 8 IUs of quadmix and 70 mcg IGF-L3. I have massive supplies so I can try for several months. I may even throw in some Andractim topically. Will keep everyone posted best I can, anyone with comments/questions welcome. Im particularly curious if i can further increase the IGF dosage.
Keep us updated but take care.
 
yakult;478271 said:
I just started my chemical Penis Enlargement routine 2 days ago; 5 IUs quadmix along with 10 IUs (70 mcg) IGF-L3. Later this week will pick up some igf-RH and switch to that. I will go 1 day on, 1 day off as to not dull the igf receptors. Today was day 2; I did 8 IUs of quadmix and 70 mcg IGF-L3. I have massive supplies so I can try for several months. I may even throw in some Andractim topically. Will keep everyone posted best I can, anyone with comments/questions welcome. Im particularly curious if i can further increase the IGF dosage.

Give us a good report and keep extra good track of your changes.
 
yakult;478271 said:
I just started my chemical Penis Enlargement routine 2 days ago; 5 IUs quadmix along with 10 IUs (70 mcg) IGF-L3. Later this week will pick up some igf-RH and switch to that. I will go 1 day on, 1 day off as to not dull the igf receptors. Today was day 2; I did 8 IUs of quadmix and 70 mcg IGF-L3. I have massive supplies so I can try for several months. I may even throw in some Andractim topically. Will keep everyone posted best I can, anyone with comments/questions welcome. Im particularly curious if i can further increase the IGF dosage.

Yakult,

Its been a couple of months.

Would you please update us regarding your cycle?
 
Powersnake12;485844 said:
Yakult,

Its been a couple of months.

Would you please update us regarding your cycle?



This is like, the one story i actually an aching to hear about. Did anyone else have experience with these types of injections? I wonder if he destroyed himself somehow.
 
Agreed, I'd like to know if he kept it up and how much he's grown. Ive done PGE1 (caverject) and oral PABA (along with hanging and pumping) for 2 months and gained more than 0.5 inch in length (and my testosterone is low). I would expect others to gain even more with high or normal range test. I very much doubt he's hurt himself doing this.

I had to stop cause i couldnt get anymore PGE1, I will definitely be back at this when
i get some.....will even start my own thread when I do.
 
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