Human Growth Hormone (Hgh) is a protein hormone of 191 amino acids that is synthesized and secreted by cells called somatrophs in the anterior pituitary gland. Human Growth Hormone is like estrogen, testosterone, progesterone, melotonin , or DHEA - one of many endocrine hormones that decline with age. Totally unique to Human Growth Hormone is the fact that even though its secretion declines with age, the body still produces the same amount of hgh as someone in their 20's. The problem lies in releasing human growth hormone from the aging pituitary cells.
Many of the bodies' hormones can be replaced with supplements to deter some of the effects of aging. But Hgh goes far beyond their scope - not only can hgh prevent biological aging, but it REVERSES a wide range of the aging process/s signs and symptoms. Human growth hormone has been scientifically shown to be able to turn back the biological clock as much as 20 years!
Human growth hormone is the most abundant hormone secreted by the pituitary gland, a process that peaks during adolescence. Gradually Hgh Human Growth Hormone secretion diminishes with age. Starting in the 20's, Hgh hormone secretion declines about 14% a decade, by 60 you only secrete 25% as much Hgh as the average 20 year old. This human growth hormone reduction, greatly contributes to the acceleration of the aging process.
How does declining Hgh effect our mind and body?
Hgh declines with age and is directly associated with many of the symptoms of aging, including: cardiovascular disease, increased body fat, osteoporosis, wrinkling, gray hair, decreased energy, reduced sexual function, impaired physical performance (muscle tone and strength), psychosocial deficits, poor sleep and others. Many of these hgh deficiency symptoms have also been found in younger adults who have hormone deficiency.
Most importantly, recent medical research has clearly demonstrated that by increasing growth hormone production, we can significantly eliminate the above symptoms, reversing the biological effects of aging and reduce body fat, increase lean muscle mass, strengthen the immune system, improve sexual performance, lower blood pressure, lower cholesterol, restore hair color and growth, increase bone tissue, strengthen the heart and increase energy.
In reviewing the benefits of human growth hormone above, it is hard to believe that Human Growth Hormone Therapy could have so many benefits. However, as you examine medical research over the last 10 years that looks into Hgh and the various bodily systems, then you are sure to understand why hgh human growth hormone therapy has been hailed as the modern day fountain of youth.
How does Human Growth Hormone Function in the body?
Hgh cycles
A key component is hgh cycles. It is important to know that hgh cycles throughout the day. As hgh cycles it is primarily released in a pulsating fashion, with serum concentrations generally lowest in the early morning and highest overnight during sleep stages III and IV. Human Growth Hormone is quickly converted by the liver into IGF-1 (also referred to as growth promoting metabolite somatomedin C), and then circulated throughout the body. IGF-1 is the factor that is measured in the blood in order to determine the level of human growth hormone secretion.
A critical concept in understanding human growth hormone deficiency is that it has two distinct types of effects:
Direct Effects are the result of human growth hormones binding its receptors on target cells. Fat cells for example, have growth hormone receptors, and growth hormone stimulates them to break down triglycerides and suppresses their ability to take up and accumulate circulating lipids.
Indirect Effects are mediated primarily by Insulin-like Growth Factor (IGF-1), a hormone that is secreted from the liver and other tissues in response to human growth hormones. A majority of the effects of human growth hormones is actually due to IGF-1 acting on target cells.
Recent hgh research has revealed that the aging pituitary cells can still secrete as much growth hormones as someone in their 20's if they are adequately stimulated. This astounding discovery is the basis of homeopathic Hgh releasers and Hgh releaser supplements, and the second type of prescription hgh that is in the process of being developed. These alternative methods to Hgh prescription injections act to stimulate the pituitary to release the human growth hormone, which is actually still produced by our bodies as we age. These types of Hgh research therapies are not based on pumping the body up with synthetic Human Growth Hormone, but with releasing human growth hormone from its dormant state in the pituitary gland itself
The Human Growth Hormone exerts its effect by binding to a single-chain plasma transmembrane glycoprotien receptor. The highest concentration of hgh receptors are found in the liver, adipose tissue, heart, kidneys, intestine, lungs, pancreas, cartilage, and skeletal muscle. This may help to explain a lot of the incredible benefits associated with increasing human growth hormone secretion in the body. As Human Growth Hormone secretion increases all the above body parts are enhanced. Human growth hormone circulates bound to plasma proteins known as growth hormone binding proteins GHBP) At physiologic concentrations, approximately 50% of Hgh Growth Hormone is protein bound. Clearance occurs rapidly through the kidneys, liver, or target tissue, with an average half life of 10-20 minutes