Each person has his or her own reaction to any kind of supplement. For men, it's less than women. His cocktail is tailored for him, but you can try to use it for yourself to see if it works. There's no adverse reaction, unless your body does react to one of the ingredients. My suggestion is to take one supplement at a time on its own, then in combo. When there's a combination of ingredients interact with the body, on top of your existing dietary intake, the reactions will definitely differ from person to person.