Chemical Avenue for Adult Testicle Enlargement?

J

j-king

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I came across this medical paper today, and was interested if anyone here is familiar with this avenue of research for testicular enlargement in adults --

https://digital.lib.washington.edu/...roidism_Induced_Macroorchidism.pdf?sequence=2

-- As I read the paper, basically the story is this. An 18-year-old was admitted for chemical therapy to correct a height deficiency. The first part of his therapy was typical and significantly improved his height. Towards the end of his therapy, at about 22, his FSH was elevated while Testosterone was depressed. The result was his testicles increased in volume by 50% -- from 20ml each to 30ml each -- in just one year. Once his testosterone level returned to normal, this increase in size was maintained. The theory behind this seems to be that FSH stimulation in the absence of testosterone leads an increase in Sertoli cells in the testicles. When FSH and testosterone are both present (eg. normal adult males), Sertoli cells do not increase.

If this approach works, it might be much safer than IGF or other chemicals that have side-effects throughout the entire body.
 
Interesting, but they did note the increased volume of the testicles. This can be accomplished by increasing sperm count too. (And the thread title suggests that we are focused upon testicular enlargement.) I have read that simply increasing sperm count enlarges the testicles as the sperm count is attributed to being one of the largest factors in determining testicular size. It is well known that zinc aids in the production, or elevation of, sperm count. But a more recent study said showed a very interesting finding. That sperm count is increased significantly more if a zinc supplement is taken in ADDITION to a folic acid supplement. If I remember correctly, there was a about an 80% increase in sperm counts in about four months of a zinc and folic acid supplementation. I think the ratio was like 12:1 (zinc to folic acid)

Tom

P.S. Oh, it was 66mg zinc and 5mg folic acid...and 74% increase in sperm counts (might as well be "double" the sperm count :D).
 
I think i will get some zinc and folic acid and see if it helps. My left testicles is smaller than the right and i don't really like it
 
**WARNING**

Not mentioned in the study that I read! Substantial supplementation of folic acid can trigger B12 deficiency. Be sure to supplement your B12 intake with the cocktail from the study as well. B12 deficiency can have some pretty bad effects over time.

Just a heads up.
 
Exactly, diseases such as korsakoff wernicke syndrome wouldn't be out of the question.
 
Well I am the one who posted the cocktail from the study to boost sperm count, so I felt responsible to also post that the cocktail could trigger B12 deficiency as well. (I wonder why the study didn't mention this?)

As a side note: Supplementing 5mg of folic acid isn't that easy. :D Most of it is sold in mcg dosages. The biggest that I have found locally are 1mg tablets. So I need to take 5 of the mg tablets just for the folic acid. The zinc is easier, as they are commonly sold as 50mg tablets.
 
clomid and novadex will make them bigger
clomid weeks 1-3 50/25/25
Novadex 1-4 40/40/20/20
 
[Update on the modified cocktail]

I have been taking the cocktail below since the 5th of this month:
75mg zinc
5mg folic acid
2mg B12

My observations:

Testes seem slightly larger and heavier.
Ejaculation volume is significantly increased beyond anything that I have ever experienced. Seems like double what I usually expel.

Who knew that a study would actually produce a cocktail that actually works? :D

The Lunatic,

Tom
 
That's good news. If you recall the "Secrets of a ���� Star Cumshot" thread, there are other supplements and techniques that radically increase ejaculation performance. Zinc was listed, but folic acid was not! If you ever want to try out a cocktail of any of those, and you include zinc, I would imagine folic acid would be improve it. The most affordable one was lots of celery and water, plus bioperine and maca.

Back to the testicle enlargement though. If they are enlarged through higher sperm count, wouldn't that mean termination of your zinc cocktail would shrink the testicles, assuming sperm count goes back down?
 
I would imagine that they would shrink if the sperm count dropped again.

As to the folic acid, that was the element that the study pointed out that significantly increased the value of the zinc supplementation. Without the increased folic acid, the zinc had significantly less effect on sperm count.
 
irspow;473210 said:
[Update on the modified cocktail]

I have been taking the cocktail below since the 5th of this month:
75mg zinc
5mg folic acid
2mg B12

My observations:

Testes seem slightly larger and heavier.
Ejaculation volume is significantly increased beyond anything that I have ever experienced. Seems like double what I usually expel.

Who knew that a study would actually produce a cocktail that actually works? :D

The Lunatic,

Tom
Click to expand...

What form of zinc are you taking? That study used Zinc sulfate, but I can't seem to find it.
 
I believe everyone is missing the point of the article. The subject suffered from hypothyroidism which caused the lack of growth. The treatment was to treat the thyroid problem which resulted in growth of the testes. At least that is how I interpreted the medicalese. Accordingly, unless you suffered from hypothyroidism, the treatment discussed in the article is not going to help you increase your testicle size.

This is similar to the issues relating to secondary hypogonadism (low testosterone during puberty) and a small dick. If you suffered from low T during puberty, it is possible to increase the size of your dick with exogenous testosterone (TRT). However, if you did not suffer with secondary hypogonadism, no amount of testosterone is going to effect the size of your dick.

Did anybody notice that the guy's stretched length was only 3 cm (1.2 inches)? Wonder why the researchers concentrated on his testicles instead of his dick?
 
awall25;474958 said:
What form of zinc are you taking? That study used Zinc sulfate, but I can't seem to find it.
Click to expand...

Awall,

I am just taking generic Zinc...the tabs I have say that they are of the gluconate form, but "Research has not determined whether differences exist among forms of zinc in absorption, bioavailability, or tolerability." Either way, the gluconate form seems to be working wonders for me. :D

From what I have read, it really doesn't matter which form is taken in this context. The different forms only vary slightly in what the percentage of elemental zinc is present, again, slightly, so I don't believe that any form will be ineffective for the purpose of the "cocktail". Other factors have much more influence on how "effective" zinc supplementation is for the individual. Absorption of zinc is significantly hampered by vegetarians for example, or those whose intake of proteins is quite low, and particularly lower for those who have high levels of phytates from eating to many grains and such.
 
irspow;475230 said:
Awall,

I am just taking generic Zinc...the tabs I have say that they are of the gluconate form, but "Research has not determined whether differences exist among forms of zinc in absorption, bioavailability, or tolerability." Either way, the gluconate form seems to be working wonders for me. :D

From what I have read, it really doesn't matter which form is taken in this context. The different forms only vary slightly in what the percentage of elemental zinc is present, again, slightly, so I don't believe that any form will be ineffective for the purpose of the "cocktail". Other factors have much more influence on how "effective" zinc supplementation is for the individual. Absorption of zinc is significantly hampered by vegetarians for example, or those whose intake of proteins is quite low, and particularly lower for those who have high levels of phytates from eating to many grains and such.
Click to expand...

Thanks, I got zinc picolinate. I'm taking

50mg zinc
1g b12
5mg folic acid

Along with some maca and fenugreek as well.
 
awall25;475233 said:
Thanks, I got zinc picolinate. I'm taking

50mg zinc
1g b12
5mg folic acid

Along with some maca and fenugreek as well.
Click to expand...

You should see significant results within about two weeks. If not I would say to bump up the zinc closer to the study's recommendation. If you are using 50mg tabs, simply take one and a half versus just one. :D

Hopefully you are taking 1 mg and not 1 g of B12 :D LOL 1 g of B12 would be like 16,600 times the normal daily intake! I have been taking 10mg B12 (regardless of my typo earlier) which is about 170% recommended daily intake. Too much B12 could lead to anxiety, palpitations, and diarrhea among other things. Just a heads up. :D

If you are taking 1mg just be sure that that is enough. If you find yourself feeling lethargic or have any signs of anemia, you may need more to counteract the cocktail.

Tom
 
irspow;475236 said:
You should see significant results within about two weeks. If not I would say to bump up the zinc closer to the study's recommendation. If you are using 50mg tabs, simply take one and a half versus just one. :D

Hopefully you are taking 1 mg and not 1 g of B12 :D LOL 1 g of B12 would be like 16,600 times the normal daily intake! I have been taking 10mg B12 (regardless of my typo earlier) which is about 170% recommended daily intake. Too much B12 could lead to anxiety, palpitations, and diarrhea among other things. Just a heads up. :D

If you are taking 1mg just be sure that that is enough. If you find yourself feeling lethargic or have any signs of anemia, you may need more to counteract the cocktail.

Tom
Click to expand...

Thanks! I am taking 1mg of B12 LOL. I take a different B complex that has some as well and I eat a lot of meat so I should be good. I forgot to add that I'm also taking Swedish flower pollen as well.

I got a ROP on Friday and started taking the supplements yesterday and I have to say something is already working.

I masturbated after a long Bathmate session Friday night and got a BJ from my girlfriend earlier today and both were way more than usual.
 
And to anyone who's reading this pumping the testicles in the Bathmate has done wonders for mine. They are a noticeably larger and hang better after only a week.

I usually start each Bathmate session pumping them for 3-5 minutes. The skin is a lot stretchier so you'll be surprised how far they stretch with no discomfort. The only issue is that the gator can leave severe marks but keeping it in the 3-5 minute range takes care of that.

Just fill the Bathmate as usual but have the gauge facing the opposite direction. Carefully push everything in and be sure to get as much of the loose skin in as possible. Then pump as normal. I pump as far as it will go and have never felt any pain.
 
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