There are a few compounds that have scientific validity in specifically reversing keritinization.
I'm doing more research to see if any counteract each other, and sourcing them.
Will follow up in time.
As far as Retin-A I strongly advise against it. Your glans will shed like crazy, but not because it is sloughing off protective skin to expose the membrane like skin that naturally covers the glans, but because you have damaged several layers of skin, and the skin that is left will be dry and brittle. The exact opposite of what you want.