Tunica albuginea and ligaments,Very different tissues each one with its particularities and similarities to other parts of the body such as the coronary arteries in the case of the tunica albuginea or the Achilles tendon in the case of the suspensory ligament, but both are reinforced with collagen and if it decreases or lowers its quality, gains are made more easily, in fact it is much more difficult and counterproductive to make gains without taking this into consideration, any biomechanical work aimed at enlarging the penis is through deformation of the tunica albuginea (yes, deformation) or stretching of the suspensory ligament leads to a increase in the collagen relative to the force used to cause this growth, I want veteran members to share their experiences with chemichal PE and what they do to reduce collagen, decrease its quality or response to the biomechanical work of each day and give their opinion on the dilemma I find myself in lately,i am thinking about giving up cigarettes and nicotine from vapes in exchange for a few months or years of pentoxifylline given its effectiveness in cases of peyronie is proven, I'm in this dilemma because whether like it or not, smoking reduces collagen and its properties in several different ways, at the same time it slows down the recovery process of the ligaments (wich is good) while pentoxifylline ends up aligning the collagen and increasing its deposit in the ligaments (which is bad), although it reduces the concentration of collagen in the tunica albuginea and combats fibrosis.
Sorry we couldn't answer your question a bit faster on this matter brother. I was out and about and the ambient noises just killed any kind of dictation to proper text. The text came out all garbage like, "Collagen is..next in line please!" or "composition of subdermal requires..your chicken order is up!"
Since you've done your homework, let's break things down even further for you and the other brothers to understand as well. It's like a whole cake full of goodness in there, but the flavors are all mixed up like a densely packed flavor bomb.
Let's stop right here. Yes. The tunica albuginea and the ligaments are a very different composition of collagen materials all together than the rest of the other tissues. If anyone did their homework on biochemistry and biodiversity of the penile molecular structures, the suspensory and the tunica albuginea collagen compositions are comprised of 80% collagen Type I, the hard and rigid type, around 15% of collagen Types II and III, the slightly more flexible collagen type that allows shrinking and flexing during preservation shrinkage state, and the 5% Type III with the combination of other androgens where the most elastin that responsible for restoration and coating of the damaged Types I and II. Unlike the rest of the penile tissues with the Type II (the fascias, skin layers) and the softer tissues (Type III elastin), the Type I is quite rigid, with a uniform structural shape, compared to a honeycomb structure.
This statement is truly a loaded statement. Why? This statement is very true for fascial and breast tissues with lower Type I collagen and higher Types II and III, where collagen is easily assimilated for faster repairs and reproduction due to the higher mobility and counter-gravitational activities in proximity to the denser structural/skeletal muscle tissues. In other words, the penis is not like the face or the breasts in terms of its supporting movements as an upper supportive layer for the highly mobile dense skeletal muscles. The penis tissues are either hard when erected with supported blood volume, or soft when it's in flaccid or rested phases. It doesn't move with the limbs, supports the limbs, nor it acts like a limb. However, we wish it could be like the third arm or the tongue to truly do some fascinating things. That's going off-topic.
I need to cut you off on this portion just a tiny bit. Yes, it does require deformation of the collagen structures, which we discuss constantly at length all the time here. Yes, we need to upshift (influence the chemical demands during a routine) or downshift (change the hormone influence during rest phases) to induce the growth rate. We are influencing growth rate by breaking down the various levels of cellular degradation and cellular regeneration. We are not influencing biochemical and biomechanical changes. We use both biochemical and biomechanical changes to trick the body to send biodiversified materials from other parts of the body, such as vitamins, minerals, oxygen, hormones, collagen production, and much much more to refocus on the penis. Biochemical triggers are caused by creating stresses along the tissues, maintaining those stress loads, generating alternative and dynamic biomechanical manipulation using different traction forces, and gravitational forces, and sustaining stress loads on the tissues at a constant state for a long period of time. This results in an influx of biological demands on the mind, requesting more resources to refocus on the penis, the last functional unit on the biological list of the human body besides waste evacuation and short-term procreation.
If you think reducing the collagen quantity to induce collagen quality, you're going completely backward. I'll explain further down.
Let's bring in all the aforementioned and incorporate your answer. I know we have a few biochemical engineers and biologists in our midst. The same for a few professors and doctors of various fields. Chime in if you like. Your identities are still well protected.
Depending on the chemicals you use for PE, any chemical you use to degrade a collagen peptide will denature the quality of the collagen overall. If you denature the collagen, the body will reject the collagen and use any complex collagen peptide to break down the chain to the proper collagen fragmentation suitable for usage. You can have 100mL of collagen peptides available, but if only 1mL among the 100mL is usable, the 99mL is pure waste. When you use chemicals to break down the collagen peptides, you are turning that 100mL of that collagen peptides to 1mL of that usable peptides. If you're using quality chemicals to enhance collagen peptide formation, you are now fortifying the 100mL of uncertainty peptides to 100mL of available peptides for immediate usage. Quality vs quantity.
Let's bring in another perspective you may consider instead. Say you're a bodybuilder, or a woman searching for a skin-perfect beauty product, do you go to a store and purchase some off-the-shelf protein drink with promised crappy collagen or a lotion with some unknown chemically induced degrader with low-quality factors to use in and on the body? It will take 10x to 1000x time more collagen induction into the rituals to get the same quality collagen materials to buildup the muscles or generate the best Types I to III collagen for optimal growth and support that will cost you an arm, a leg, and possibly your penis to get.
To sum it all up, quality collagen is required to rebuild, and not degrade existing strong collagen and dump cheap collagen to repair. It's like breaking down a sturdy fortified stone fortress and using construction foam to build up a larger less sturdy fortress.
If you take a few steps back, nicotine and the compounds used for vapes and cigarettes, including secondary burnt-off compounds (second hand smoking), not only destroy your vascular system, but also degrade key hormones that support your entire body function. Just cutting out vaping/cigarettes already gives you a better fighting chance with PE. However, the lingering of the various compounds from the period you've vaped/smoked required to be reduced from your system in order for your PE to be successful. When you mention pentoxifylline, yes, it will expedite the assistance by migration the compounds out of your bloodstream a bit faster, but at this point, how much is in your system for the drug to assist with the detoxification? This is where the phrase, "Only time can tell" comes into play.
Yes, Peroynie's disease is proven, and it's also proven that PE can help. But it requires you to have good clean health to bring PE into success. You can't eat, drink, and smoke craps and call PE good. PE, like any other lifestyle, requires a good and wholesome approach. You can't expect a marathon runner to be in peak condition with nothing but energy drinks and processed foods. @DLD excluded. That guy is a case of miracle on its own that we are all still scratching our heads on how he survived to this very point in life. If he donated his body to sciences when he moved on to the heavenly realm decades from now, we probably discover miracle drugs from his body.
I'm sorry to say, but this is putting the cart before the horse. There were many discussions like this in the past, and many have tried your methods of thinking even to this very day, but none of those came back and claimed that they were successful. Why? Because it's counter-logic, counter-intuitive, and counter-biological.
This is a whole different kind of game together brother. We can go into further details about collagen concentration to combat fibrosis and fibromyalgia, but the reverse statement is true where an increase of specific collagen assists with the recovery of nerves, renewal, and redevelopment of nerves, as well as new quality tissue growth to replace overabundant of useless low-quality tissue concentration. Fibrosis is like a massive arm with super strong muscle tissues that can't even move a few inches. This is where the reduction of collagen plays in your favor. The same is true with fibromyalgia, where there are weakened muscle tissues that do not support the nerves and blood vessels. In both cases, quality collagen to rebuild the tissues at a proper concentration is required. But that can be discussed in a different topic as it can get very intensive.
Since you've done your homework, let's break things down even further for you and the other brothers to understand as well. It's like a whole cake full of goodness in there, but the flavors are all mixed up like a densely packed flavor bomb.
Let's stop right here. Yes. The tunica albuginea and the ligaments are a very different composition of collagen materials all together than the rest of the other tissues. If anyone did their homework on biochemistry and biodiversity of the penile molecular structures, the suspensory and the tunica albuginea collagen compositions are comprised of 80% collagen Type I, the hard and rigid type, around 15% of collagen Types II and III, the slightly more flexible collagen type that allows shrinking and flexing during preservation shrinkage state, and the 5% Type III with the combination of other androgens where the most elastin that responsible for restoration and coating of the damaged Types I and II. Unlike the rest of the penile tissues with the Type II (the fascias, skin layers) and the softer tissues (Type III elastin), the Type I is quite rigid, with a uniform structural shape, compared to a honeycomb structure.
This statement is truly a loaded statement. Why? This statement is very true for fascial and breast tissues with lower Type I collagen and higher Types II and III, where collagen is easily assimilated for faster repairs and reproduction due to the higher mobility and counter-gravitational activities in proximity to the denser structural/skeletal muscle tissues. In other words, the penis is not like the face or the breasts in terms of its supporting movements as an upper supportive layer for the highly mobile dense skeletal muscles. The penis tissues are either hard when erected with supported blood volume, or soft when it's in flaccid or rested phases. It doesn't move with the limbs, supports the limbs, nor it acts like a limb. However, we wish it could be like the third arm or the tongue to truly do some fascinating things. That's going off-topic.
I need to cut you off on this portion just a tiny bit. Yes, it does require deformation of the collagen structures, which we discuss constantly at length all the time here. Yes, we need to upshift (influence the chemical demands during a routine) or downshift (change the hormone influence during rest phases) to induce the growth rate. We are influencing growth rate by breaking down the various levels of cellular degradation and cellular regeneration. We are not influencing biochemical and biomechanical changes. We use both biochemical and biomechanical changes to trick the body to send biodiversified materials from other parts of the body, such as vitamins, minerals, oxygen, hormones, collagen production, and much much more to refocus on the penis. Biochemical triggers are caused by creating stresses along the tissues, maintaining those stress loads, generating alternative and dynamic biomechanical manipulation using different traction forces, and gravitational forces, and sustaining stress loads on the tissues at a constant state for a long period of time. This results in an influx of biological demands on the mind, requesting more resources to refocus on the penis, the last functional unit on the biological list of the human body besides waste evacuation and short-term procreation.
If you think reducing the collagen quantity to induce collagen quality, you're going completely backward. I'll explain further down.
Let's bring in all the aforementioned and incorporate your answer. I know we have a few biochemical engineers and biologists in our midst. The same for a few professors and doctors of various fields. Chime in if you like. Your identities are still well protected.
Depending on the chemicals you use for PE, any chemical you use to degrade a collagen peptide will denature the quality of the collagen overall. If you denature the collagen, the body will reject the collagen and use any complex collagen peptide to break down the chain to the proper collagen fragmentation suitable for usage. You can have 100mL of collagen peptides available, but if only 1mL among the 100mL is usable, the 99mL is pure waste. When you use chemicals to break down the collagen peptides, you are turning that 100mL of that collagen peptides to 1mL of that usable peptides. If you're using quality chemicals to enhance collagen peptide formation, you are now fortifying the 100mL of uncertainty peptides to 100mL of available peptides for immediate usage. Quality vs quantity.
Let's bring in another perspective you may consider instead. Say you're a bodybuilder, or a woman searching for a skin-perfect beauty product, do you go to a store and purchase some off-the-shelf protein drink with promised crappy collagen or a lotion with some unknown chemically induced degrader with low-quality factors to use in and on the body? It will take 10x to 1000x time more collagen induction into the rituals to get the same quality collagen materials to buildup the muscles or generate the best Types I to III collagen for optimal growth and support that will cost you an arm, a leg, and possibly your penis to get.
To sum it all up, quality collagen is required to rebuild, and not degrade existing strong collagen and dump cheap collagen to repair. It's like breaking down a sturdy fortified stone fortress and using construction foam to build up a larger less sturdy fortress.
If you take a few steps back, nicotine and the compounds used for vapes and cigarettes, including secondary burnt-off compounds (second hand smoking), not only destroy your vascular system, but also degrade key hormones that support your entire body function. Just cutting out vaping/cigarettes already gives you a better fighting chance with PE. However, the lingering of the various compounds from the period you've vaped/smoked required to be reduced from your system in order for your PE to be successful. When you mention pentoxifylline, yes, it will expedite the assistance by migration the compounds out of your bloodstream a bit faster, but at this point, how much is in your system for the drug to assist with the detoxification? This is where the phrase, "Only time can tell" comes into play.
Yes, Peroynie's disease is proven, and it's also proven that PE can help. But it requires you to have good clean health to bring PE into success. You can't eat, drink, and smoke craps and call PE good. PE, like any other lifestyle, requires a good and wholesome approach. You can't expect a marathon runner to be in peak condition with nothing but energy drinks and processed foods. @DLD excluded. That guy is a case of miracle on its own that we are all still scratching our heads on how he survived to this very point in life. If he donated his body to sciences when he moved on to the heavenly realm decades from now, we probably discover miracle drugs from his body.
I'm sorry to say, but this is putting the cart before the horse. There were many discussions like this in the past, and many have tried your methods of thinking even to this very day, but none of those came back and claimed that they were successful. Why? Because it's counter-logic, counter-intuitive, and counter-biological.
This is a whole different kind of game together brother. We can go into further details about collagen concentration to combat fibrosis and fibromyalgia, but the reverse statement is true where an increase of specific collagen assists with the recovery of nerves, renewal, and redevelopment of nerves, as well as new quality tissue growth to replace overabundant of useless low-quality tissue concentration. Fibrosis is like a massive arm with super strong muscle tissues that can't even move a few inches. This is where the reduction of collagen plays in your favor. The same is true with fibromyalgia, where there are weakened muscle tissues that do not support the nerves and blood vessels. In both cases, quality collagen to rebuild the tissues at a proper concentration is required. But that can be discussed in a different topic as it can get very intensive.
Thanks for this post. I could not say it better
there are several reports of smokers who gained from PE, I had gains before smoking and continued to have them after starting to smoke, if you could send the link to any of these discussions I would appreciate it, what I said was based on articles, it is a fact that smoking delays ligament healing and weakens ligaments and tendons which in theory would be beneficial for hanging, when I started hanging I was already a smoker so I can't say from my own experience, I gained 1/4 inch in bpfsl with 2lb in 3 months which took about of a year to be translated into erect gains, after this period I increased another 1lb and didn't make any more permanent gains, I recently increased another 1lb and I'm deciding which approach would be more effective, I'm thinking about doing vacuum hanging instead of compressed
This is a good point, because if I could smoke and keep the endothelium and smooth muscle of my penis healthy I probably wouldn't be in this dilemma,I wonder if the key to increasing my gains could be more spontaneous erections, especially during sleep
In my opinion, collagen is the reason you can have increased growth. Take, for example, one of the best Collagens out there: Bulbs Collagen. It's specific for the types that @oldandlively talked about. After a workout, if you take it, it will go to re-structure the collagen production in a good manner which is essential for PE.
Now, I love smoking too dude. I love it more than a pussy but... smoking means killing your efforts.
Unless you are young (15-28), You cant achieve rock-solid erections which are essential for PE.
But, thats only my opinion and I am not veteran.
Now, I love smoking too dude. I love it more than a pussy but... smoking means killing your efforts.
Unless you are young (15-28), You cant achieve rock-solid erections which are essential for PE.
But, thats only my opinion and I am not veteran.
I can only get completely hard and maintain an erection with cialis or viagra, without them even if I get hard I can't maintain an erection, I rarely have spontaneous erections without using anything, it seems to me that I damaged the endothelium more than I reduced the collagen in the tunica, if you search a little you will see an article known in our area about anti-lox
leaving aside aging the only accessible stuff that have anti-lox activity is cigarettes
cigarettes i guess are my anti-lox. Growing4Squirting
Well-known member
I occasionally vape when im in stressful mood, and one thing i noticed is my girth has suffered since i started ( not long ago almost two months, never did before nor consumed cigarettes).
Flaccid girth diminished a little bit so is the erected girth, and i haven't done any girth exercises before so this decreases is from my girth starting point.
Growing4Squirting
Well-known member
These discussions are in the medical and biochemical symposia, or discussion sites for medical, chemical, biological, and various other professionals. You can join in on the discussions if you like. You have to create accounts all over the place to get the discussions you need. Medscape is a great start for medical. CMA Docs is another one. Science Forums (net) is a great site where we come together to dump our info for discussions. SciencesConf (or worldwide sciences conferences) is a good hangout for those who drink too much coffee with hot topics. You have various worldwide top Ivy League universities discussion rooms you can also sign up for, including molecular and biochemistry hot demanded topics to sink your teeth into.
You want to base on publication articles, we can go there too.
This is just what had been discovered in the recent days. We can go even more gruesome portions of collagen atrophy and biomolecular degeneration in more recent published articles if you like to read.
Yes, this is true, but that the same time, improper balance of weakened ligaments and tissues and weight loading can in fact injure your ligaments and tissues beyond repairs, or outpace the emergency repairs that result in cellular deformation to the point of unable to repair. You end up causing yourself your own Peyronie's issues.
This is actually a common gain without having to go into the collagen degradation route. You will actually gain by promoting healthy collagen growth over degrading the collagen growth. Simple Type 1 and Type 2 collagen deformation through traction load manipulation, with lateral force contortion, is more than enough.
To get erections, or sudden woods, that comes from having good testosterone concentration in your blood stream. Two of the brothers here that talked to me during the PE went into a secondary puberty stage for their penile growth. Their penile erections become so hard throughout the night and even during the day that they have to milk themselves constantly to reduce the amount of erectile tension. It's about playing smart with PE routines to invoke the body to promote new growths that induce the erectile quality you're looking for.
As @kriskros also mentioned, it's about the age range and the health lifeline you build up.
I remember this one, and it got dropped off pretty quickly. If you continued to research on it, you discovered that it was discovered through cancer patients. My brother was one of them. The collagen synthesis reduced, and he aged, like many others, 10 years in less than a few months. Uncontrolled methods, and it happened constantly, will produce detrimental effects.
Read through this article first and see if you can see the nuances of the the anti-LOX potency that is controlled vs uncontrolled.
If you don't think it doesn't effect human in the long run, just read this article for the time being to understand the long term side effects for human. By the way, long term can be as short as a 3 months period.
There are much much more. Dig deeper brother. I'm proud of you to go this deep with the pre-surface research. Dig much deeper and wider.
It's as bad, if not as worst, as smoking. Vaping, in terms of just adding flavonoids and essences, is not as bad. However, the mixtures have gotten very bad nowadays. The smoke is no longer light but thickened for the effects of heavy smoking. That itself does a number on the lungs due to the sticky resin generated for the thicker smoke-like effects. The flavor blending now contain not only what's in the old cigarettes, the compounds being used to create the high, such as tainted CBD and THC, added with the chemicals known to cause high rate of cancers and cellular irregularities, are now loaded in the "Get your ultimate high" cartridges. One of the patients that was with me in the hospital when I was prepped for surgery was suffering from vape meltdown and convulsed like a demon possessed in the adjacent emergency room.
Growing4Squirting
Well-known member
Crazy, the main reason i use the vape is because its not as "dirty" as cig.
The liquid can sometimes be inhaled and that's also a dangerous thing.
I used this temporary until im strong enough to carry on with life.
I guess i have to quit. It's my last hang up. I've quit everything but smoking remains my last vice. Going to need a lot of prayer to quit.
You guys can research on the vape contents from the cartridges. There are safe versions out there, and there are enhanced versions containing large volume of glycol, glycerin, and various additional thickeners and additives for the flavors and highs will be your factor of either "kill you faster", "kill you instantly", or "you can go a bit longer". The one that had the cardiac episode was probably using a tainted cartridge with very high specific components. She was doing fancy smokery in the front of the building before she came in to sit down with her friends. I could smell that strawberry and unicorn craps that everyone enjoyed, and the hint of concentrated HTC was in the scent. If I hang around her, I would have a scent of strawberry and male odor to bring into the ER surgical floor. She ended up in the surgical floor before I was and she wasn't even a "patient" on the planned list. She became a patient by induction.
There is no particular branding. This is where you have to dig up the formulation for each maker. The same maker can make dozens of cartridges, and each cartridge is loaded from the light materials to the death-await-you materials. You have to look into each version of the maker's cartridge for their components. If they can't offer you the list of materials and concentration, you know you're getting tainted cartridges from who-knows-where.