Thanks
@oldandlively - I would be interested in the biochemistry breakdown for certain. Hmmm...I could combine DMSO with HMB to make a topical as well since DMSO supercharges anything it is combined with.
I agree with the water assessment for certain (I'm sure you have read the book "Your Body's Many Cries for Water")...The only struggle I have is that as a truck driver if I load up on water...I will need to make more stops thus being late in my deliveries. I could get a portable urinal.
Right now I need to cut down on buying supplements since the chief CFO (my wife) stated we need to cut back on spending.
I can understand the endeavor and the budgets required to keep your body in shape. You are not only investing in keeping your health in check, but you are also keeping your manhood in shape. They are working in tandem in a symbiotic dance. My wife was the same, and I am the CFO in the house. She has her botox and beauty products, while I keep us all healthy with proper supplements, eating, and equipment to keep us alive a little longer. But I do understand about life's constraints in the family budgets. However, do explain to her that it's more for overall health than wastes. The old saying, "spend a pound, save a penny" comes into play.
Now, on with the biochemistry lesson. You already research about the horny goat weed extract. You probably landed on chemical extraction from the weed known as icariin, or ICA for short. This is the main component of the extract that helps with the erectogenic role, or get your penis up by assisting the healing/modification of the corpus cavernosa. However, the biochemical role for this compound is the XX folds (still to be determined) in the PDE5 inhibitory activity (degeneration of nerves and blood vessels in the penis) by activating the two hydroxyethyl ethers moieties. Now, freeze on the term "hydroxyethyl ethers". I'll bring it in along the way.
Now, for the HMB, which stands of beta-hydroxy-beta-methylbutyrate. HMB is an aide for ergogenic, which has a 70% focus on recovery or repair over the performance and stamina. It acts as a defender or inhibitor to the ubiquitin-proteasome proteolytic pathway, which identified as a the cause specific degradation of intracellular proteins. HUH? Tissues, muscles, and nerve degeneration issues. But why HMB? Because HMB is generated in the mitrochondrial portion of the cells after breaking down leucine, which is the amino acids designated for growth and repair consumed from eggs, fish, meats, etc. By the way, at this point, super charging your mitochondrial powerhouse in your cells before receiving HMB and ICA will enhance the effects. Ah...
Red light therapy.
But what does HMB and ICA has to do with anything? During cellular stresses, tissue-nerve damages, or intramuscular responses to repair, HMB acts as a anticatabolic agent, or the activation of protein synthesis, pulled in by the cellular bodies to perform regeneration processes. During this period, when hydroxyethyl ethers are available, the β-hydroxy-β-methylbutyric acid from the HMB breakdown processes binds to the hydroxyethyl ethers so synergize the repair effects on the stressed cellular structures. This is more prevalent to the nerve repair cycles due to degeneration or damages.
As I described earlier, the lower extremities don't get the sufficient blood flow to deliver the essentials. Notice how your finger nails grow much faster than your toe nails? Notice a cut at the bottom of the feet tends to be longer healing than the cut on the upper body? Think about that for a moment. During preservation mode after the age of 30, your body no longer rely on the reproductive instinct and refocus on survival instinct. That means your penis gets the least amount of the nutrients comparable to the rest of your body. Sperm counts drop every passing year after the age of 27. Why is that? Ponder that for a moment.
So, what's the approach during the PE journey? Easy. Refocus the nutrient delivery system. How?
- Keep your body heathy. For men, our testosterone level must be average or high. This promotes the human growth hormone production to ensure tissues and internal muscular fibers to constantly regenerate. Libido is a side benefit as your body believes the genetic must be passed down from the high bodily functions at optimal level like when you're in your prime.
- Make sure the bioavailability of the essentials are abundant. You're not longer being triggered as survival mode but reengaging into reproductive mode. Good constant diet to prevent your body from triggering that survival mode.
- Force delivery pathway of the bioavailability of essentials. This is where the l-citrulline malate comes into play. Nitric oxide hyper drive your blood throughout the entire system. Just by drinking it, you're not getting the full benefit. A little exercise goes a long way. You don't have to run a marathon or climb a mountain. Just simple activities to rev up your heart rate to maximize that nitric oxide. It also assist with energy efficiency by delivering the essentials without the additional costs of cellular activities through the TCA cycle. If I have to go into major details, you and the brothers may be blanking out very soon.
- But why Vit D3 as well? Commercial HMB is from calcium HMB monohydrate. Vitamin D3, much more efficient to absorbed than D2, leaches the HMB molecular components must faster and more effective than using HMB alone, delivering both the needed calcium to the bones and the organs needed the calcium as part of the synthase processes. On top of that, l-citrulline malate further boost the delivery of the calcium to the far reaches of the body as the malate is a precursor for the calcium absorption.
As you can see, they work through a synergistic dance with one another. But is there a true balance between the three of them? No. Your body will take what it needs and toss the rest. Reduce what's not desired and keep the level of bioavailability essentials for the body to use when needed. Since horny goat weed extract has a biomass of 20% phytoestrogen compound, by reference, we reduce 20% from the total volume for daily suggested requirements. HMB daily recommendation is 4 grams to 6 grams for aging generations. 3 grams is more than enough as your good dietary consumption will offset that 1 to 3 grams of essential leucine that gets converted to HMB naturally.
I think I covered sufficiently. Let me know if you want further dive into this topic.
