My preferred med is Cialis, less gastric side effects, less sinus side effects, less flushing side effects, onset of action less than 1 hour, duration of action is about 72 hours. Whenever I take an ed med, I find that I have to take a sinus pill, a benadryl, a pepcid, Maalox, and some Advil, LOL. I guess it's an ED cocktail, ROFLMAO @ myself.