I will inform any brother on here…you MUST use pharma grade DMSO to a completely clean and dry penis. And ZERO residuals (ie: soaps, lotions, etc.) left on your tool. DO NOT come in contact with any polyester (like putting your undies on after) or any other synthetic thing that comes in contact with your dick. Nothing. IF you combine anything with DMSO, it simply has to be 100% pure, organic etc, or you will drive unwanted shit into your dick. Ensure you spot test the DMSO. Allow to completely and thoroughly dry. I have used it and just walked around in the birthday suit for about 45 minutes. Then dressed. Just some personal advise.