Low Serotonin causes premature ejaculation?

aidarkk31 said:

The neurotransmitter serotonin (5HT) plays a central role in the ejaculatory response. Low levels of serotonin in specific areas of the brain may lead premature ejaculation

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Dapoxitene for instance (SSRI for delaying ejaculation):

Works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay.



Therefore:
^Increasing serotonin levels in the brain.

Dapoxetine for premature ejaculation

My personal combo if I am feeling too horny;​

• 25mg of lidocaine applied on glans + frenulum (Spread evenly, do not apply beyond the corona of the glans)​

​

• Dapoxetine: 30 - 60mg. (45min prior to intercourse) By the way, combine it with grapefruit juice (Since the drug its metabolized with CYP2D6 & CYP3A4 enzymes)​

​

Medicinal importance of grapefruit juice and its interaction with various drugs

(If feeling too horny, and wanting to impress my chick of course. If not, just cum and repeat. And don't forget about her.)​

Jürgen88 said:

View attachment 1829564

Dapoxitene for instance (SSRI for delaying ejaculation):

Works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay.

View attachment 1829565
View attachment 1829566
Therefore:
^Increasing serotonin levels in the brain.

Dapoxetine for premature ejaculation

My personal combo if I am feeling too horny;​

• 25mg of lidocaine applied on glans + frenulum (Spread evenly, do not apply beyond the corona of the glans)​

View attachment 1829568 View attachment 1829569​

Remember to use some carrier oil, like PG/vegetable glycerin/Low % DMSO
(Propylene glycol, wont irritate the skin, I use PG + ethanol to brew RU58841 for Androgenic alopecia (Better safe than sorry) , it doesn't irritate the scalp)(Always patch test on forearm)

(After applied & dried, clean with tap-water/distilled water, for any left residue/taste, enjoy having sex)

(Facilitates multiple rounds, plus added benefit that if she cant open her mouth wide enough, you wont really care about her giving you a toothy BJ)

• Dapoxetine: 30 - 60mg. (45min prior to intercourse) By the way combine it with grapefruit juice (Since the drug its metabolized with (CYP2D6 & CYP3A4 enzymes)​

View attachment 1829567​

Grapefruit juice its a mild agonist of CYP3A4 enzymes, prolonging the half life.

View attachment 1829570

Medicinal importance of grapefruit juice and its interaction with various drugs

(If feeling too horny, and wanting to impress my chick of course. If not, just cum and repeat. And don't forget about her.)​

Some women tend to overexcite seeing a man cum multiple times. That's a benefit in some cases, but thinking logically feels humiliating in a sense, but who the fuck cares, as long as you make her orgasm too, we are both even. ¯\_(ツ)_/¯

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• 3.6$ * 20g (20.000 mg)= 72$

• Any other website 10 tabs - 30mg each = 15$ = 30*10 = 300mg for 15$.

​

Jürgen88 said:

Yeah, it is a prescription drug.

But there is always an exception to the rule...

I buy it from alldaychemist when "german" websites are out of stock (Which is always...)(Any website that you see online that sells this stuff, literally imports it from Asia)

But of course there are other websites, that sell the raw powder, so you can cap it yourself, and literally you can buy kg of that stuff for a fraction of the cost:

View attachment 1829571
(Machine for capping)

View attachment 1829572
(Example of raw powder website)

• 3.6$ * 20g (20.000 mg)= 72$

• Any other website 10 tabs - 30mg each = 15$ = 30*10 = 300mg for 15$.

See the price difference?


Besides paying 30-60$ for something that takes literally 0.10$ to be produced, makes no sense to me.

Is like paying 250k($) for a brand new lamborghini when an r8 has the same engine and literally costs less money. (Huracan line-up)

//

Side note:

You can combine it with bioperine too, 5-10mg. That will increase bioavailability of any drug. Now combine with grapefruit juice and you have the perfect combo.

More bang for your buck.

Bioperine and different herbs found to increase oral bioavailability of certain drugs​

"Piperine was found to increase bioavailability of different drugs ranging from 30% to 200%."

View attachment 1829573​

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Castor said:

unfortunately, i am affected by premature ejaculation, and sometimes depending on how aroused i am can blow in the first 20 seconds of intercourse. i dont know if i have ever lasted longer than 5 minutes. i've been reading up on it everywhere, but every article is contradicting the next. I happened to come across a site that said low serotonin is the cause of premature ejaculation, but they were also trying to sell a product which increases it. it also says that protein may inhibit serotonin production, i take protein shakes regularly with my bodybuilding program, could this be a real cause, or is it all just bs? Any tips on improving endurance?

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